Present positions
Professor of Neurosurgery / UEF
University of Eastern Finland 2004 –
Chairman of Neurosurgery / KUH
NeuroCenter / Kuopio University Hospital 2004 –
KUH Neuro-Oncology Group
Previous
positions
Neurosurgery / Helsinki University
Hospital
*
Resident 1978 – 85
* Staff
Neurosurgeon 1986 – 91
*
Lecturer of Neurosurgery 1992 – 00
* Acting
Professor of Neurosurgery 1994 – 95
* Head of
Department 2001 – 2004
Academic
degrees
MD 1977 – Medical School /
Kuopio University / Finland
Neurosurgeon 1985 –
Neurosurgery / Helsinki University / Finland
PhD 1986 – Neurosurgery and
Neuropathology / Helsinki University
*
Intracranial Meningioma: Factors Affecting Recurrence / Prof Matti
Haltia
Docent of Neurosurgery 1995 –
Helsinki University
Professor of Neurosurgery 2004
– UEF University of Eastern Finland
Visiting
Professor
2001–2 Neurosurgery / Brigham
and Women’s Hospital / Harvard Medical School
Main
scientific positions of trust
Cancer Society of Finland – Evaluation
Committees of Cancer Research Grants
* Member
– Basic Cancer Research 2009 – 2011
*
Chairman – Clinical Cancer Research 2011 –
Scandinavian Neurosurgical Society
*
Lecturer in Training Courses for neurosurgery residents 2003 –
EANS European Association of
Neurosurgical Societies
* Member
of EANS Neurooncology Committee 1996 – 03
* Member
of EANS Research Committee 2003 –
*
Lecturer in EANS Training Courses for neurosurgery residents
Acta Neurochirurgica / EANS journal
*
Editorial board member 2009 –
Research and
development / UEF University of Eastern Finland 2004 –
Kuopio Intracranial Aneurysm Research
Group www.uef.fi/ns
Kuopio NPH and Early Alzheimer Disease
Group www.uef.fi/nph
Development of pre / intraoperative
brain mapping www.medi-imaging.org
Development of pre / intraoperative brain mapping
Scientific
original articles in international peer-reviewed journals
125 in total – 54 on intracranial
aneurysms – 71 on neuro-oncology
Supervision
of PhD theses
6 completed –12 in progress
Adviser for
medical technology manufacturers
Elekta Neuromag (former Neuromag), Helsinki www.elekta.com
* neurosurgical applications of magnetoencephalography (MEG)
NexStim, Helsinki www.nexstim.com
* contact Henri Hannula
* neurosurgical applications of navigated transcranial
magnetic stimulation
Clinical
experience in neuro-oncology
Member of multidisciplinary neuro-oncology group
Helsinki University Hospital
2000 – 4
Kuopio University Hospital
2004 –
Microsurgery of intracranial tumours supplemented by brain mapping
techniques
preoperative functional brain mapping
intraoperative electric stimulation
mapping
awake craniotomy
Stereotactic techniques
biopsies and catheter placements
intratumoural implantation of 1-125
isotope seeds
Stereotactic radiotherapy with linear accelerator
Helsinki University Hospital
1996 – 2004
Kuopio University Hospital
2004 –
KUH CyberKnife since III 2012
Inherited CNS tumour traits
Neurofibromatosis 1 (NF1)
Neurofibromatosis 2 (NF2)
von Hippel-Lindau disease (VHL)
Author of 71 scientific articles on neuro-oncology
Author of domestic neuro-oncology chapters / Duodecim Kustannus
Keskushermoston kasvaimet /
Neurologia-kirja 2011
Kallonsisäiset kasvaimet /
Kirurgia-kirja 2010
Keskushermoston kasvaimet /
Syöpätaudit-kirja 2007
Stereotaktinen sädehoito kallon alueelle
/ Duodecim-lehti 2008
Peer-reviewed
original articles
H-index = 36
Articles
cited >100 times = 12
2011
Anna P, Niemelä M, van Popta J, Matti P, Kangasniemi M, Rinne J, Jääskeläinen J,
Hernesniemi J. Management of 251 patients with dural arteriovenous
fistulas - Helsinki and Kuopio experience 1944-2006. (submitted)
Pyykkö OT, Helisalmi S, Koivisto AM, Mölsä JAA, Rummukainen J, Nerg O,
Alafuzoff I, Savolainen S, Soininen H, Jääskeläinen JE,
Rinne J, Leinonen V, Hiltunen M. APOE4 predicts amyloid-β in cortical
brain biopsy but exhibits a nonexistant role in idiopathic normal
pressure hydrocephalus. Journal of Neurology Neurosurgery Psychiatry
(re-submitted)
Koivisto AM, Alafuzoff I, Savolainen S, Sutela A, Rummukainen J,
Vanninen R, Jääskeläinen
JE,
Soininen H, Rinne J, Leinonen V. Subsequent dementia in initially
shunt-responsive patients with idiopathic normal pressure
hydrocephalus. Journal of Neurology Neurosurgery Psychiatry (submitted)
Gaál
EA, Salo P, Kristiansson K, Rehnström K, Kettunen J, Niemelä
M,
Nieminen MS, Sinisalo J, Lokki M-L, Jula A, Raitakari O, Lehtimäki T,
Eriksson JG, Widen E, Günel M, Kurki M, von und zu Fraunberg M, Jääskeläinen JE,
Hernesniemi J, The International Consortium for Blood Pressure
Genome-wide Association Studies (ICBP-GWAS), Palotie A, Salomaa V,
Perola M. Intracranial Aneurysm risk locus 5q23•2 is associated with
elevated systolic blood pressure. PloS Genetics (re-submitted)
125.
TT Seppälä, O Nerg, AM Koivisto, Rummukainen J, Puli LM,
Zetterberg H, Pyykkö, OT, Helisalmi S, Alafuzoff I, Hiltunen M, Jääskeläinen JE,
Rinne J, Soininen H, Leinonen V, Herukka S-K. Ventricular and lumbar
CSF biomarkers for Alzheimer’s disease correlate with cortical brain
biopsy findings. Neurology (in press)
124. Yasuno K, Bakircioglu M, Low S-K, Bilguvar K, Gaál E, Ruigrok YM,
Niemela M, Hata A, Bijlenga P, Kasuya H, Jääskeläinen JE,
Krex D, Auburger G, Simon M, Krischek B, Ozturk AK, Mane S, Steinmetz
H, Zembutsu H, Inoue I, Palotie A, Cambien F, Nakamura Y, Lifton RP,
Murat Günel M. A common variant near the endothelin receptor
type
A (EDNRA) gene is associated with intracranial aneurysm risk. PNAS 2011
www.pnas.org/cgi/doi/10.1073/pnas.1117137108
123. Leinonen V, Koivisto AM, Alafuzoff I, Pyykkö OT, Rummukainen J,
von und zu Fraunberg M, Jääskeläinen
JE,
Soininen H, Rinne, Savolainen S. Cortical brain biopsy in long-term
prognostication of 468 patients with possible normal pressure
hydrocephalus. Neurodegenerative Diseases (in press)
122. Huttunen T, Riihinen A, Pukkala E, von und zu Fraunberg M,
Koivisto T, Ronkainen A, Rinne J, Sankila R, Jääskeläinen JE.
Increased relative risk of lung cancer in 2 904 patients with saccular
intracranial aneurysm disease in Eastern Finland. Neuroepidemiology (in
press)
121. Soppi V, Karamanakos PN, Koivisto T, Vanninen R,
Jaaskelainen JE, Rinne J. A randomized outcome study of enteral versus
intravenous nimodipine in 171 patients after acute aneurysmal
subarachnoid hemorrhage. World Neurosurgery (in press)
120. Lindgren A, Huttunen T, Saavalainen T, Riihinen A, Kurki MI,
Koivisto T, Ronkainen A, Rinne J, Hernesniemi J, Jääskeläinen JE,
von und zu Fraunberg M. Increased incidence of aneurysmal subarachnoid
hemorrhage on Sundays and Mondays in 1862 patients from Eastern
Finland. Neuroepidemiology (in press)
119. Coco K, Tossavainen K, Jääskeläinen JE,
Turunen H. Support for Traumatic Brain Injury Patients' Family Members
in Neurosurgical Nursing: A Systematic Review. J Neurosci Nurs
2011;43:337-348
118. Leinonen V, Koivisto AM, Savolainen S, Rummukainen J, Sutela A,
Vanninen R, Jääskeläinen
JE,
Soininen H, Alafuzoff I. Post-mortem findings in 10 patients with
presumed normal pressure hydrocephalus and review of the
literature.Neuropathol Appl Neurobiol 2011 Jun 23. doi:
10.1111/j.1365-2990.2011.01195.x.
117. Leinonen V, Menon LG, Carroll RS, Dello Iacono D, Grevet J, Jääskeläinen JE,
Black PM. Cerebrospinal fluid biomarkers in idiopathic normal pressure
hydrocephalus. Int J Alzheimers Dis 2011;2011:312526
116. Kurki MI, Paananen J, Storvik M, Ylä-Herttuala S, Jääskeläinen JE,
von Und Zu Fraunberg M, Wong G, Pehkonen P. TAFFEL: Independent
Enrichment Analysis of gene sets. BMC Bioinformatics 2011;12:171
115. Kurki MI, Häkkinen SK, Frösen J, Tulamo R, von und zu Fraunberg M,
Wong G, Tromp G, Niemelä M, Hernesniemi J, Jääskeläinen JE,
Ylä-Herttuala S. Upregulated signaling pathways in ruptured human
saccular intracranial aneurysm wall: an emerging regulative role of
Toll-like receptor signaling and nuclear factor-κB, hypoxia-inducible
factor-1A, and ETS transcription factors. Neurosurgery 2011;68:1667-75
114. Huttunen T, von und Zu Fraunberg M, Koivisto T, Ronkainen A, Rinne
J, Sankila R, Seppä K, Jääskeläinen
JE.
Long-term excess mortality of 244 familial and 1502 sporadic one-year
survivors of aneurysmal subarachnoid hemorrhage compared with a matched
Eastern Finnish catchment population. Neurosurgery 2011;68:20-7
2010
113.
Leinonen V, Koivisto AM, Savolainen S, Rummukainen J, Tamminen JN,
Tillgren T, Vainikka S, Pyykkö OT, Mölsä J, Fraunberg M, Pirttilä T, Jääskeläinen JE,
Soininen H, Rinne J, Alafuzoff I. Amyloid and tau proteins in cortical
brain biopsy and Alzheimer's disease. Ann Neurol 2010;68:446-53
IF = 9.3
112.
Lehecka M, Dashti R, Laakso A, van Popta JS, Romani R, Navratil O,
Kivipelto L, Kivisaari R, Foroughi M, Kokuzawa J, Lehto H, Niemelä M,
Rinne J, Ronkainen A, Koivisto T, Jääskelainen JE, Hernesniemi J.
Microneurosurgical management of anterior choroid artery aneurysms.
World Neurosurg 2010;73:486-99
111. Säisänen L, Könönen M, Julkunen P, Määttä S, Vanninen R, Immonen
A, Jutila L, Kälviäinen R, Jääskeläinen
JE,
Mervaala E. Non-invasive preoperative localization of primary motor
cortex in epilepsy surgery by navigated transcranial magnetic
stimulation. Epilepsy Res 2010;92(2-3):134-44
110. Leu M, Humphreys K, Surakka I, Rehnberg E, Muilu J, Rosenström P,
Almgren P, Jääskeläinen
J,
Lifton RP, Kyvik KO, Kaprio J, Pedersen NL, Palotie A, Hall P, Grönberg
H, Groop L, Peltonen L, Palmgren J, Ripatti S. NordicDB: a Nordic pool
and portal for genome-wide control data. Eur J Hum Genet 2010;18:1322-6
109.
Karamanakos PN, Koivisto T, Vanninen R, Khallaf M, Ronkainen A,
Parviainen I, Manninen H, von und zu Fraunberg M, Morgan MK,
Jaaskelainen JE, Hernesniemi J, Rinne J. The impact of endovascular
management on the outcome of aneurysmal subarachnoid hemorrhage in the
elderly in eastern Finland. Acta Neurochir 2010;152:1493-502
108.
Yasuno K, Bilguvar K, Bijlenga P, Low SK, Krischek B, Auburger G, Simon
M, Krex D, Arlier Z, Nayak N, Ruigrok YM, Niemelä M, Tajima A, von und
zu Fraunberg M, Dóczi T, Wirjatijasa F, Hata A, Blasco J,
Oszvald
A, Kasuya H, Zilani G, Schoch B, Singh P, Stüer C, Risselada R, Beck J,
Sola T, Ricciardi F, Aromaa A, Illig T, Schreiber S, van Duijn CM, van
den Berg LH, Perret C, Proust C, Roder C, Ozturk AK, Gaál E, Berg D,
Geisen C, Friedrich CM, Summers P, Frangi AF, State MW, Wichmann HE,
Breteler MM, Wijmenga C, Mane S, Peltonen L, Elio V, Sturkenboom MC,
Lawford P, Byrne J, Macho J, Sandalcioglu EI, Meyer B, Raabe A,
Steinmetz H, Rüfenacht D, Jääskeläinen
JE,
Hernesniemi J, Rinkel GJ, Zembutsu H, Inoue I, Palotie A, Cambien F,
Nakamura Y, Lifton RP, Günel M. Genome-wide association study of
intracranial aneurysm identifies three new risk loci. Nat Genet
2010;42:420-5
107. Karamanakos PN, Jaaskelainen JE, Alafuzoff I,
Pirinen E, Vanninen R, Silvennoinen S, Sankilampi U, Immonen A.
Malignant giant cell tumor in the posterior fossa of a neonate. J
Neurosurg Pediatr 2010;5:277-82
106. Huttunen T, von und zu
Fraunberg M, Frösen J, Lehecka M, Tromp G, Helin K, Koivisto T, Rinne
J, Ronkainen A, Hernesniemi J, Jääskeläinen JE.
Saccular intracranial aneurysm disease: distribution of site, size, and
age suggests different etiologies for aneurysm formation and rupture in
316 familial and 1454 sporadic eastern Finnish patients. Neurosurgery
2010;66:631-8
105. Celik O, Piippo A, Romani R, Navratil O, Laakso A, Lehecka M,
Dashti R, Niemelä M, Rinne J, Jääskeläinen JE,
Hernesniemi J. Management of dural arteriovenous fistulas - Helsinki
and Kuopio experience. Acta Neurochir Suppl 2010;107:77-82
2009
104.
Karamanakos PN, Varis J, Ronkainen A, Koivisto T, Rinne J, Jaaskelainen
JE. Chronic subdural haematoma after endoscopic treatment of a
supracellar arachnoid cyst. Acta Neurol Belg 2009;109:149-51
103. Romani R, Lehecka M, Gaal E, Toninelli S, Celik O, Niemelä M,
Porras M, Jääskeläinen
J,
Hernesniemi J. Lateral supraorbital approach applied to olfactory
groove meningiomas: experience with 66 consecutive patients.
Neurosurgery 2009;65:39-52
102. Myllymaa S, Myllymaa K, Korhonen H, Töyräs J, Jääskeläinen JE,
Djupsund K, Tanila H, Lappalainen R. Fabrication and testing of
polyimide-based microelectrode arrays for cortical mapping of evoked
potentials. Biosens Bioelectron 2009;24:3067-72
101. Lehecka M,
Dashti R, Romani R, Celik O, Navratil O, Kivipelto L, Kivisaari R, Shen
H, Ishii K, Karatas A, Lehto H, Kokuzawa J, Niemelä M, Rinne J,
Ronkainen A, Koivisto T, Jääskelainen JE, Hernesniemi J.
Microneurosurgical management of internal carotid artery bifurcation
aneurysms. Surg Neurol 2009;71:649-67
2008
100.
Bilguvar K, Yasuno K, Niemelä M, Ruigrok YM, von Und Zu Fraunberg M,
van Duijn CM, van den Berg LH, Mane S, Mason CE, Choi M, Gaál E, Bayri
Y, Kolb L, Arlier Z, Ravuri S, Ronkainen A, Tajima A, Laakso A, Hata A,
Kasuya H, Koivisto T, Rinne J, Ohman J, Breteler MM, Wijmenga C, State
MW, Rinkel GJ, Hernesniemi J, Jääskeläinen JE,
Palotie A, Inoue I, Lifton RP, Günel M. Susceptibility loci for
intracranial aneurysm in European and Japanese populations. Nat Genet
2008;40:1472-7
99. Leinonen V, Alafuzoff I, Aalto S, Suotunen T, Savolainen S, Någren
K, Tapiola T, Pirttilä T, Rinne J, Jääskeläinen JE,
Soininen H, Rinne JO. Assessment of beta-amyloid in a frontal cortical
brain biopsy specimen and by positron emission tomography with carbon
11-labeled Pittsburgh Compound B. Arch Neurol 2008;65:1304-9
98. Lehecka M, Dashti R, Hernesniemi J, Niemelä M, Koivisto T,
Ronkainen A, Rinne J, Jääskeläinen
J.
Microneurosurgical management of aneurysms at the A2 segment of
anterior cerebral artery (proximal pericallosal artery) and its
frontobasal branches. Surg Neurol 2008;70:232-46
97. Lehecka M, Dashti R, Hernesniemi J, Niemelä M, Koivisto T,
Ronkainen A, Rinne J, Jääskeläinen
J. Microneurosurgical management of aneurysms at A3
segment of anterior cerebral artery. Surg Neurol 2008;70:135-51
96. Lehecka M, Dashti R, Hernesniemi J, Niemelä M, Koivisto T,
Ronkainen A, Rinne J, Jääskeläinen
J.
Microneurosurgical management of aneurysms at A4 and A5 segments and
distal cortical branches of anterior cerebral artery. Surg Neurol
2008;70:352-67
95. Hernesniemi J, Dashti R, Lehecka M, Niemelä M, Rinne J, Lehto H,
Ronkainen A, Koivisto T, Jääskeläinen
JE. Microneurosurgical management of anterior
communicating artery aneurysms. Surg Neurol 2008;70:8-28
94. Lehecka M, Lehto H, Niemelä M, Juvela S, Dashti R, Koivisto T,
Ronkainen A, Rinne J, Jääskeläinen
JE,
Hernesniemi JA. Distal anterior cerebral artery aneurysms: treatment
and outcome analysis of 501 patients. Neurosurgery 2008;62:590-601
93.
Helgadottir A, Thorleifsson G, Magnusson KP, Grétarsdottir S,
Steinthorsdottir V, Manolescu A, Jones GT, Rinkel GJ, Blankensteijn JD,
Ronkainen A, Jääskeläinen
JE,
Kyo Y, Lenk GM, Sakalihasan N, Kostulas K, Gottsäter A, Flex A,
Stefansson H, Hansen T, Andersen G, Weinsheimer S, Borch-Johnsen K,
Jorgensen T, Shah SH, Quyyumi AA, Granger CB, Reilly MP,
Austin
H, Levey AI, Vaccarino V, Palsdottir E, Walters GB, Jonsdottir T,
Snorradottir S, Magnusdottir D, Gudmundsson G, Ferrell RE,
Sveinbjornsdottir S, Hernesniemi J, Niemelä M, Limet R, Andersen K,
Sigurdsson G, Benediktsson R, Verhoeven EL, Teijink JA, Grobbee DE,
Rader DJ, Collier DA, Pedersen O, Pola R, Hillert J, Lindblad B,
Valdimarsson EM, Magnadottir HB, Wijmenga C, Tromp G, Baas AF, Ruigrok
YM, van Rij AM, Kuivaniemi H, Powell JT, Matthiasson SE, Gulcher JR,
Thorgeirsson G, Kong A, Thorsteinsdottir U, Stefansson K. The same
sequence variant on 9p21 associates with myocardial infarction,
abdominal aortic aneurysm and intracranial aneurysm. Nat Genet
2008;40:217-24
2007
92. Mäkelä JP, Forss N, Jääskeläinen
J, Kirveskari E, Korvenoja A, Paetau R.
Magnetoencephalography in neurosurgery. Neurosurgery 2007;61(1
Suppl):147-64
91. Dashti R, Hernesniemi J, Lehto H, Niemelä M, Lehecka M, Rinne J,
Porras M, Ronkainen A, Phornsuwannapha S, Koivisto T, Jääskeläinen JE.
Microneurosurgical management of proximal anterior cerebral artery
aneurysms. Surg Neurol 2007;68:366-77
90.
Weinsheimer S, Goddard KA, Parrado AR, Lu Q, Sinha M, Lebedeva ER,
Ronkainen A, Niemelä M, Khusnutdinova EK, Khusainova RI, Helin K, Jääskeläinen JE,
Sakovich VP, Land S, Kuivaniemi H, Tromp G. Association of kallikrein
gene polymorphisms with intracranial aneurysms. Stroke 2007;38:2670-6
89. Larjavaara S, Mäntylä R, Salminen T, Haapasalo H, Raitanen J, Jääskeläinen J,
Auvinen A. Incidence of gliomas by anatomic location. Neuro Oncol
2007;9:319-25
88. Dashti R, Hernesniemi J, Niemelä M, Rinne J, Lehecka M, Shen H,
Lehto H, Albayrak BS, Ronkainen A, Koivisto T, Jääskeläinen JE.
Microneurosurgical management of distal middle cerebral artery
aneurysms. Surg Neurol 2007;67:553-63
87.
Dashti R, Hernesniemi J, Niemelä M, Rinne J, Porras M, Lehecka M, Shen
H, Albayrak BS, Lehto H, Koroknay-Pál P, de Oliveira RS, Perra G,
Ronkainen A, Koivisto T, Jääskeläinen
JE. Microneurosurgical management of middle cerebral
artery bifurcation aneurysms. Surg Neurol 2007;67:441-56
86. Frösen J, Pitkäniemi J, Tulamo R, Marjamaa J, Isoniemi H, Niemelä
M, Jääskeläinen
J,
Lokki ML, Matinlauri I. Association of fatal aneurysmal subarachnoid
hemorrhage with human leukocyte antigens in the Finnish population. Hum
Immunol 2007;68:100-5
85. Lehecka M, Niemelä M, Seppänen J, Lehto H, Koivisto T, Ronkainen A,
Rinne J, Sankila R, Jääskeläinen
J,
Hernesniemi J. No long-term excess mortality in 280 patients with
ruptured distal anterior cerebral artery aneurysms. Neurosurgery
2007;60:235-40
84. Dashti R, Rinne J, Hernesniemi J, Niemelä M,
Kivipelto L, Lehecka M, Karatas A, Avci E, Ishii K, Shen H, Peláez JG,
Albayrak BS, Ronkainen A, Koivisto T, Jääskeläinen JE.
Microneurosurgical management of proximal middle cerebral artery
aneurysms. Surg Neurol 2007;67:6-14
83. Havu-Aurén K, Kiiski J, Lehtiö K, Eskola O, Kulvik M, Vuorinen V,
Oikonen V, Vähätalo J, Jääskeläinen J,
Minn H. Uptake of 4-borono-2-[18F]fluoro-L-phenylalanine in sporadic
and neurofibromatosis 2-related schwannoma and meningioma studied with
PET. Eur J Nucl Med Mol Imaging 2007;34:87-94
IF = 4.5
2006
82.
Hernesniemi J, Niemelä M, Dashti R, Karatas A, Kivipelto L, Ishii K,
Rinne J, Ronkainen A, Peláez JG, Koivisto T, Kivisaari R, Shen H,
Lehecka M, Frösen J, Piippo A, Avci E, Jääskeläinen JE.
Principles of microneurosurgery for safe and fast surgery. Surg Technol
Int 2006;15:305-10
81. Tulamo R, Frösen J, Junnikkala S, Paetau A, Pitkäniemi J,
Kangasniemi M, Niemelä M, Jääskeläinen
J,
Jokitalo E, Karatas A, Hernesniemi J, Meri S. Complement activation
associates with saccular cerebral artery aneurysm wall degeneration and
rupture. Neurosurgery 2006;59:1069-76
80. Mäkelä JP, Forss N, Jääskeläinen
J, Kirveskari E, Korvenoja A, Paetau R.
Magnetoencephalography in neurosurgery. Neurosurgery 2006;59:493-510
79. Korvenoja A, Kirveskari E, Aronen HJ, Avikainen S, Brander A,
Huttunen J, Ilmoniemi RJ, Jääskeläinen
JE,
Kovala T, Mäkelä JP, Salli E, Seppä M. Sensorimotor cortex
localization: comparison of magnetoencephalography, functional MR
imaging, and intraoperative cortical mapping. Radiology 2006;241:213-22
78. Frösen J, Marjamaa J, Myllärniemi M, Abo-Ramadan U, Tulamo R,
Niemelä M, Hernesniemi J, Jääskeläinen
J.
Contribution of mural and bone marrow-derived neointimal cells to
thrombus organization and wall remodeling in a microsurgical murine
saccular aneurysm model. Neurosurgery 2006;58:936-44
77. Frösen J, Piippo A, Paetau A, Kangasniemi M, Niemelä M, Hernesniemi
J, Jääskeläinen
J.
Growth factor receptor expression and remodeling of saccular cerebral
artery aneurysm walls: implications for biological therapy preventing
rupture. Neurosurgery 2006 Mar;58(3):534-41
76. Nagy L, Ishii K, Karatas A, Shen H, Vajda J, Niemelä M, Jääskeläinen J,
Hernesniemi J, Toth S. Water dissection technique of Toth for opening
neurosurgical cleavage planes. Surg Neurol 2006;65(1):38-41
2005
75.
Timonen M, Kankaanranta L, Lundbom N, Collan J, Kangasmäki A,
Kortesniemi M, Häkkinen AM, Lönngren A, Karjalainen S, Rasilainen M,
Leinonen J, Huitti T, Jääskeläinen
J,
Kouri M, Savolainen S, Heikkinen S. 1H MRS studies in the Finnish boron
neutron capture therapy project: detection of 10B-carrier,
L-p-boronophenylalanine-fructose. Eur J Radiol 2005;56:154-9
74.
Hernesniemi J, Niemelä M, Karatas A, Kivipelto L, Ishii K, Rinne J,
Ronkainen A, Koivisto T, Kivisaari R, Shen H, Lehecka M, Frösen J,
Piippo A, Jääskeläinen
JE.
Some collected principles of microneurosurgery: simple and fast, while
preserving normal anatomy: a review. Surg Neurol 2005;64:195-200
73.
Niemelä M, Koivisto T, Kivipelto L, Ishii K, Rinne J, Ronkainen A,
Kivisaari R, Shen H, Karatas A, Lehecka M, Frösen J, Piippo A, Jääskeläinen J,
Hernesniemi J. Microsurgical clipping of cerebral aneurysms
after the ISAT Study. Acta Neurochir Suppl 2005;94:3-6
2004
72. Tynninen O, Carpén O, Jääskeläinen
J,
Paavonen T, Paetau A. Ezrin expression in tissue microarray of primary
and recurrent gliomas. Neuropathol Appl Neurobiol 2004;30:472-7
71. Frösen J, Piippo A, Paetau A, Kangasniemi M, Niemelä M, Hernesniemi
J, Jääskeläinen
J.
Remodeling of saccular cerebral artery aneurysm wall is associated with
rupture: histological analysis of 24 unruptured and 42 ruptured cases.
Stroke 2004;35:2287-93
70. Kouri M, Kankaanranta L, Seppälä T,
Tervo L, Rasilainen M, Minn H, Eskola O, Vähätalo J, Paetau A,
Savolainen S, Auterinen I, Jääskeläinen
J,
Joensuu H. Undifferentiated sinonasal carcinoma may respond to
single-fraction boron neutron capture therapy. Radiother Oncol
2004;72:83-5
69. Sirén V, Antinheimo JP, Jääskeläinen J,
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